EPIDEMIOLOGICAL, CLINICAL ASPECTS AND ASSOCIATED FACTORS WITH DERMATOLOGICAL MANIFESTATIONS DURING VIRAL HEPATITIS B AND C AT THE BORGOU / ALIBORI DEPARTMENTAL CHU IN 2023

Résumé

Introduction: Dermatological manifestations can occur during a systemic disease such as viral hepatitis B and C. The objective of this research was to study the frequency and factors associated with dermatological manifestations during viral hepatitis B and C at CHUD B/A in 2023.

Framework and study methods: This was a cross-sectional, descriptive study with analytical aim with prospective data collection which took place from February 2023 to May 2023 in the Dermatology-Venerology and Hepato-Gastroenterology departments of CHUD B/A in Parakou, Benin. The data collected were recorded and analyzed using Epi data version 3.1 and IBM SPSS version 21 software. The significance threshold was p=0.05.

Results: A total of 135 patients were involved in the study. Forty-five patients presented at least one dermatological manifestation, representing a prevalence of 33.3%. The average age of the patients was 36.8 ± 9.87 years. More than half of the patients (55.6%) were male and most of them had a secondary education (37.8%) and were married (88.9%). Infectious dermatoses were the most common in a proportion of 37.8%, dominated by candidiasis (17.8%) and pityriasis versicolor (13.3%). However, pruritus sine materia was the most common dermatological diagnosis (31.1%). There were also immuno-allergic dermatoses (17.7%) represented by eczema (4.4%), aquagenic pruritus (4.4%) and urticaria (6.7%), inflammatory dermatoses (8.9%) represented by acne (11.1%). The associated factors identified were: long duration of liver disease (p=0.011), use of lightening cosmetics (p=0.005) and absence of antiviral treatment (p=0.010).

Conclusion: Dermatological manifestations during viral hepatitis B and C are frequent at CHUD B/A. They are dominated by infectious dermatoses and pruritus sine materia. Treatment of viral hepatitis would be a protective factor.